Full Citation
Title: Analgesic use during pregnancy and risk of infant leukaemia: A Children's Oncology Group study
Citation Type: Book, Whole
Publication Year: 2011
ISBN:
ISSN: 00070920
DOI: 10.1038/sj.bjc.6606046
NSFID:
PMCID:
PMID: 21157452
Abstract: BACKGROUND: Infant leukaemia is likely initiated in utero.\n\nMETHODS: We examined whether analgesic use during pregnancy was associated with risk by completing telephone interviews of the mothers of 441 infant leukaemia cases and 323 frequency-matched controls, using unconditional logistic regression.\n\nRESULTS: With the exception of a reduced risk for infant acute myeloid leukaemias with non-aspirin non-steroidal anti-inflammatory drugs (NSAID) use early in pregnancy (odds ratios=0.60; confidence intervals: 0.37-0.97), no statistically significant associations were observed for aspirin, non-aspirin NSAIDs, or acetaminophen use in early pregnancy or after knowledge of pregnancy.\n\nCONCLUSION: Overall, analgesic use during pregnancy was not significantly associated with the risk of infant leukaemia.
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Authors: Ognjanovic, Simona; Blair, Cindy K.; Spector, Logan G.; Robison, Leslie L.; Roesler, Michelle; Ross, Julie A.
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Publisher Location:
Pages: 532-536
Volume: 104
Edition:
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