MPC Member Publications

This database contains a listing of population studies publications written by MPC Members. Anyone can add a publication by an MPC student, faculty, or staff member to this database; new citations will be reviewed and approved by MPC administrators.

Full Citation

Title: Environmental Risk Factors for Childhood Central Nervous System Tumors: an Umbrella Review

Citation Type: Journal Article

Publication Year: 2022

ISBN: 0123456789

ISSN: 2196-2995

DOI: 10.1007/S40471-022-00309-5

Abstract: Childhood central nervous system tumors (cCNSt) are the most common solid tumors in individuals under 20 years old, yet environmental risk factors are not well established. Therefore, we conducted an umbrella review to summarize the current literature on risk factors related to cCNSt. Childhood exposure to ionizing radiation from medical devices was the strongest risk factor. There was evidence of positive associations with several other factors, including maternal age, birth weight, and pesticide exposure. Conversely, maternal folic acid supplementation during pregnancy and having childhood allergic conditions were inversely associated with cCNSt. Few studies assessed associations by cCNSt histological subtypes and none by molecular subtypes. Exposure assessments were limited to data linkages, parental recall via questionnaires, or measurements at diagnosis. Because cCNSt are highly heterogeneous, future research is needed to examine risk factors by molecular and histological subtypes and to apply novel, unbiased exposure assessments.

Url: https://link.springer.com/article/10.1007/s40471-022-00309-5

User Submitted?: No

Authors: Hoang, Thanh T; Whitcomb, Elizabeth; Reardon, Erin E; Logan, ยท; Spector, G; Lupo, Philip J; Scheurer, Michael E; Williams, Lindsay A

Periodical (Full): Current Epidemiology Reports 2022

Issue:

Volume: 1

Pages: 1-23

Countries:

IPUMS NHGIS NAPP IHIS ATUS Terrapop