MPC Member Publications

This database contains a listing of population studies publications written by MPC Members. Anyone can add a publication by an MPC student, faculty, or staff member to this database; new citations will be reviewed and approved by MPC administrators.

Full Citation

Title: Maternal pregnancy events and exposures and risk of hepatoblastoma: A Children's Oncology Group (COG) study

Citation Type: Book, Whole

Publication Year: 2013

ISBN: 0002-9262

ISSN: 18777821

DOI: 10.1016/j.canep.2012.12.005

PMID: 23312454

Abstract: Background: Hepatoblastoma is a rare childhood liver cancer with an obscure etiology, however it is potentially associated with selected pregnancy events and hepatoblastoma risk in offspring. Methods: Adjusted unconditional logistic regression estimated odds ratios (OR) and corresponding 95% confidence intervals (CI) for self-reported pregnancy events and medication use in a sample of mothers of 383 childhood hepatoblastoma cases and 387 controls. Results: Risk of hepatoblastoma was significantly associated with maternal first trimester weight gain (OR. =. 1.02; 95% CI 1.00, 1.04 per 1. lb increase and nearly significantly with maternal multivitamin use (OR. =. 0.73; 95% CI 0.51, 1.03). Hepatoblastoma was not associated with other maternal weight changes, maternal illness or medication use during pregnancy. Conclusion: We found little evidence that maternal illness or most medication use during pregnancy are associated with hepatoblastoma in offspring. © 2012 Elsevier Ltd.

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Authors: Musselman, Jessica R B; Georgieff, Michael; Ross, Julie A.; Tomlinson, Gail E.; Feusner, James H.; Krailo, Mark D.; Spector, Logan G.

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Pages: 318-320

Volume: 37

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IPUMS NHGIS NAPP IHIS ATUS Terrapop