Full Citation

Title: Policy support and potential black-market use in response to a reduced nicotine standard: responses following a 12-week open-label clinical trial

Citation Type: Journal Article

Publication Year: 2025

ISBN: 2025059450

ISSN: 0964-4563

DOI: 10.1136/TC-2025-059450

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PMCID:

PMID: 40691047

Abstract: A reduced nicotine standard (RNS) could be one of the most significant tobacco control policies in history. The recent proposed rule issued by the U.S. Food and Drug Administration for an RNS is based on evidence showing that very low nicotine content (VLNC) cigarettes potentially decrease smoking rates, resulting in a substantial decline in smoking-related disease.1 One potential concern of an RNS is the potential to contribute to a pervasive black market for normal nicotine content (NNC) cigarettes.2 Furthermore, support for an RNS is likely to be discussed as part of the rationale for (or against) its implementation. To address these concerns, the present study describes the intent to seek black-market cigarettes and policy support for an RNS among adults after non-blinded assignment to VLNC cigarettes in a 12-week clinical trial. Participants were randomised to receive either VLNC or NNC cigarettes and also had access to non-combusted tobacco/nicotine products (eg, e-cigarettes, oral tobacco) in an experimental marketplace (methods reported elsewhere).3 The full demographics of the VLNC arm of …

Url: https://tobaccocontrol.bmj.com/content/early/2025/07/21/tc-2025-059450

Url: https://tobaccocontrol.bmj.com/content/early/2025/07/21/tc-2025-059450.abstract

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Authors: Hackworth, Emily E; Carroll, Dana Mowls; Donny, Eric C; Denlinger-Apte, Rachel L; Hatsukami, Dorothy

Periodical (Full): Tobacco Control

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Pages: tc-2025-059450

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