MPC Member Publications

This database contains a listing of population studies publications written by MPC Members. Anyone can add a publication by an MPC student, faculty, or staff member to this database; new citations will be reviewed and approved by MPC administrators.

Full Citation

Title: Caffeine and blood pressure response: sex, age, and hormonal status.

Citation Type: Journal Article

Publication Year: 2010

ISSN: 1931-843X

DOI: 10.1089/jwh.2009.1664

PMID: 20500126

Abstract: PURPOSE The pressor effect of caffeine has been established in young men and premenopausal women. The effect of caffeine on blood pressure (BP) remains unknown in postmenopausal women and in relation to hormone replacement therapy (HRT) use. MATERIALS AND METHODS In a randomized, 2-week cross-over design, we studied 165 healthy men and women in 6 groups: men and premenopausal women (35-49 yrs) vs. men and postmenopausal women (50-64 yrs), with postmenopausal women divided into those taking no hormone replacements (HR), estrogen alone, or estrogen and progesterone. Testing during one week of the study involved 6 days of caffeine maintenance at home (80 mg, 3x/day) followed by testing of responses to a challenge dose of caffeine (250 mg) in the laboratory. The other week involved ingesting placebos on maintenance and lab days. Resting BP responses to caffeine were measured at baseline and at 45 to 60 min following caffeine vs placebo ingestion, using automated monitors. RESULTS Ingestion of caffeine resulted in a significant increase in systolic BP in all 6 groups (4 +/- .6, p < 0.01). Diastolic BP significantly increased in response to caffeine in all (3 +/- .4, p < 0.04) but the group of older men (2 +/- 1.0, p = 0.1). The observed pressor responses to caffeine did not vary by age. CONCLUSIONS Caffeine resulted in an increase in BP in healthy, normotensive, young and older men and women. This finding warrants the consideration of caffeine in the lifestyle interventions recommended for BP control across the age span.

Url: http://www.ncbi.nlm.nih.gov/pubmed/20500126

Url: http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=PMC2940460

User Submitted?: No

Authors: Farag, Noha H; Whitsett, Thomas L; McKey, Barbara S; Wilson, Michael F; Vincent, Andrea S; Everson-Rose, Susan A; Lovallo, William R

Periodical (Full): Journal of women's health (2002)

Issue: 6

Volume: 19

Pages: 1171-6

Countries:

IPUMS NHGIS NAPP IHIS ATUS Terrapop