Full Citation
Title: Epidemiology of childhood acute myeloid leukemia
Citation Type: Book, Whole
Publication Year: 2013
ISBN: 6053126071
ISSN: 15455009
DOI: 10.1002/pbc.24464
NSFID:
PMCID:
PMID: 23303597
Abstract: Although leukemia is the most common childhood cancer diagnosis, the subtype, acute myeloid leukemia (AML), is less common and fewer etiologic studies exist. This review summarizes the major risk factors for AML. We searched the literature using PubMed for articles on childhood AML and reviewed 180 articles. While few risk factors are definitive, we identified several with consistent evidence of a possible effect. Thorough analysis of genetic and epigenetic factors is missing from this literature and methodological issues are unresolved. Future studies should more closely examine causal mechanisms, improve exposure measurement, and include analysis using genetic and epigenetic factors.
Url: http://doi.wiley.com/10.1002/pbc.24464
User Submitted?: No
Authors: Puumala, Susan E.; Ross, Julie A.; Aplenc, Richard; Spector, Logan G.
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Publisher Location:
Pages: 728-733
Volume: 60
Edition:
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