MPC Member Publications

This database contains a listing of population studies publications written by MPC Members. Anyone can add a publication by an MPC student, faculty, or staff member to this database; new citations will be reviewed and approved by MPC administrators.

Full Citation

Title: 20. In an Ethnically/Racially and Socioeconomically Diverse Sample of Adolescents, do Weight Stigma, Family Functioning, and Parenting Practices Predict Disordered Eating Behaviors Eight Years Later?

Citation Type: Journal Article

Publication Year: 2022

ISSN: 1054-139X

DOI: 10.1016/J.JADOHEALTH.2022.01.133

Abstract: between 15e17-years old had stopped gender-affirming medications compared with 10.6% of patients who started GnRHa between 9e14-years, though this difference did not reach statistical significance. Insurance sponsor's rank (family income), birth-assigned sex, and the presence of mood disorders were not associated with cessation rates. Within 2 years of starting GnRHa, 83.2% (95%CI: 70.2 e 94.4%) of patients had started gender-affirming hormones; within 8 years of starting GnRHa, this number increased to 91.6% (95%CI 81.6 e100%). Younger patients had a greater delay in starting gender-affirming hormones. Insurance sponsor's rank, birth-assigned sex, and the presence of mood disorders were not associated with initiation of gender-affirming hormones. Conclusions: Contrary to concerns, GnRHa use did not inevitably lead to use of gender-affirming hormones. One out of twelve TGD adolescents who started GnRHa to address gender dysphoria subsequently stopped treatment. Sources of Support: None. Purpose: StRONG was a multicenter randomized clinical trial of refeeding in hospitalized adolescents and young adults with malnutrition secondary to anorexia nervosa (AN) and atypical anorexia nervosa (AAN) (ClinicalTrials.gov #NCT02488109). At end-of-treatment, higher calorie refeeding (HCR) was more efficacious and less costly than lower calorie refeeding (LCR). Here we compare efficacy of HCR in AAN vs. AN. Methods: Participants were N¼120, 12-24 yr-olds with > 60% median Body Mass Index (%mBMI) and medical instability. AAN was defined as %mBMI >85% at baseline. Meal-based HCR began 2000 calories/day (kcal/d) and advanced 200 kcal/d; LCR began 1400 kcal/d and advanced 200 kcal every other day (no tube feeding). Efficacy was defined as time to restore a 6-point Medical Stability Index (MSI): heart rate (HR) 45 bpm; systolic blood pressure (SBP) 90 mmHg, temperature 35.6 C, orthostatic increase in HR 35 bpm and decrease SBP 20 mmHg, and 75% median BMI (%mBMI). Main outcome was days to restore MSI, compared between groups with unpaired t-test. Exploratory moderator analyses examined the interaction between refeeding treatment and diagnosis on key outcomes (time to recover heart rate and weight gain). Weight gain was defined as change in %mBMI. Results: Modified intention to treat analyses included N¼111. Mean age was 16.5 (2.5) yrs, 43% had AAN. Upon admission, %mBMI was 95.2 (9) in AAN vs. 76.5 (5.9) in AN, p<.001. Upon discharge, %mBMI was 98.3 (8.9) in AAN vs. 82.2 (5.3) in AN, p<.001. MSI was restored fastest in patients with AN refed by HCR [7.1 (5.4) days], whereas medical stability required three additional days to restore in patients with AAN [10.1 (5.3) days, p<0.01]. Diagnosis (AAN or AN) and treatment (HCR or LCR) interacted to weaken the effect of refeeding on HR recovery [B¼3.76 (.572,6.95), p¼0.021] and weight gain [B¼039 (.006,072), p¼0.021], which was 0.3% mBMI per day slower (p¼0.005) and 2.6% mBMI less overall (p¼0.009) in AAN than AN. Conclusions: While HCR is more efficacious than LCR for refeeding in AN, it may contribute to underfeeding in AAN. source) and four family variables (family functioning , parental connection, parental monitoring, and parental psychological control). The outcome, UWCB (e.g. fasting, vomiting, laxative use), was self-reported by young adults eight years later. Logistic regression models estimated odds ratios (OR) and 95% confidence intervals (CI) of UWCB for four weight stigma predictors and four family predictors. Models were adjusted for sociodemographic characteristics, baseline UWCB, and baseline BMI percentile, and predictors were modeled separately. Results: In analyses adjusted for sociodemographic characteristics, all weight stigma and family variables during adolescence longitudinally predicted significantly higher odds of UWCB eight years later. After additionally adjusting for baseline UWCB and baseline BMI percentile, two weight stigma variables (weight teasing from family [OR: 1.42, 95% CI: 1.08, 1.87] and hurtful weight-related comments from family [OR: 1.34, 95% CI: 1.06, 1.70]) and one family variable (poor family functioning [OR: 1.44, 95% CI: 1.14, 1.81]) remained significantly associated with subsequent UWCB. Conclusions: Findings indicate that there are long-term consequences , across major development periods, of weight teasing from family, hurtful weight-related comments from family, and low family 2022 SAHM Annual Meeting / Journal of Adolescent Health 70 (2022) S1eS32 S11

Url: http://www.jahonline.org/article/S1054139X22001926/fulltext

Url: http://www.jahonline.org/article/S1054139X22001926/abstract

Url: https://www.jahonline.org/article/S1054-139X(22)00192-6/abstract

User Submitted?: No

Authors: Garber, Andrea K; Cheng, Jing; Accurso, Erin C; Adams, Sally H; Buckelew, Sara M; Kapphahn, Cynthia J; Kreiter, Anna A; Le Grange, Daniel; Machen, Vanessa I; Moscicki, Anna-Barbara; Wilson, Leslie; Golden, Neville H; Hooper, Laura; Puhl, Rebecca; Eisenberg, Marla E; Berge, Jerica M; Neumark-Sztainer, Dianne

Periodical (Full): Journal of Adolescent Health

Issue: 4

Volume: 70

Pages: S11-S12

Countries:

IPUMS NHGIS NAPP IHIS ATUS Terrapop