MPC Member Publications

This database contains a listing of population studies publications written by MPC Members. Anyone can add a publication by an MPC student, faculty, or staff member to this database; new citations will be reviewed and approved by MPC administrators.

Full Citation

Title: Racial and ethnic disparities in pediatric cancer incidence among children and young adults in the United States by single year of age

Citation Type: Journal Article

Publication Year: 2021

ISSN: 1097-0142

DOI: 10.1002/CNCR.33678

Abstract: Background: Incidence rates of pediatric cancers in the United States are typically reported in 5-year age groups, obscuring variation by single year of age. Additionally, racial and ethnic variation in incidence is typically presented in broad categories rather than by narrow age ranges. Methods: The Surveillance, Epidemiology, and End Results (SEER) 18 data (2000-2017) were examined to calculate frequencies and age-adjusted incidence rates among individuals aged birth to 39 years. Incidence rate ratios (IRRs) and 95% confidence intervals (95% CIs) were estimated as the measure of association for rate comparisons by race and Hispanic origin overall and by single year of age. Results: Several histologic types showed substantial variation in race/ethnicity-specific and overall rates by single year of age. Overall, Black children and young adults experienced substantially decreased incidence of acute lymphoid leukemia (IRR, 0.52; 95% CI, 0.49-0.55) compared to Whites, and this decreased incidence was strongest at ages 1 through 7 years and 16 through 20 years. Hispanic individuals experienced decreased overall incidence of Hodgkin lymphoma (IRR, 0.50; 95% CI, 0.48-0.52) and astrocytoma (IRR, 0.54; 95% CI, 0.52-0.56) and increased risk of acute lymphoblastic leukemia (IRR, 1.46; 95% CI, 1.42-1.51) compared to non-Hispanic Whites, and the increased risk was strongest at ages 10 through 23 years. Substantial decreased risk across many tumor types was also observed for Asian/Pacific Islanders and American Indian/Alaska Natives. Conclusions: Examination of incidence rates for pediatric cancers by narrow age groups may provide insights regarding etiological differences in subgroups. Additionally, variation in age-specific incidence rates by race and ethnicity may enable hypothesis generation on drivers of disparities observed.

Url: https://acsjournals.onlinelibrary.wiley.com/doi/full/10.1002/cncr.33678

Url: https://acsjournals.onlinelibrary.wiley.com/doi/abs/10.1002/cncr.33678

Url: https://acsjournals.onlinelibrary.wiley.com/doi/10.1002/cncr.33678

User Submitted?: No

Authors: Marcotte, Erin L.; Domingues, Allison M.; Sample, Jeannette M.; Richardson, Michaela R.; Spector, Logan G.

Periodical (Full): Cancer

Issue:

Volume: 0

Pages: 2021

Countries:

IPUMS NHGIS NAPP IHIS ATUS Terrapop