Full Citation
Title: Distance to Care Predicts Clinical Trial Enrollment on COG ALL Clinical Trials: A Report from the Children's Oncology Group
Citation Type: Journal Article
Publication Year: 2023
ISBN:
ISSN: 0006-4971
DOI: 10.1182/BLOOD-2023-182477
NSFID:
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PMID:
Abstract: <p>Introduction: Equitable participation in clinical trials for all populations is essential to ensure the generalizability of clinical trial results. Historical data suggest that the majority of pediatric patients are enrolled on a trial when treated at a cooperative group institution and minoritized patients are proportionally represented. We proposed to evaluate clinical trial enrollment on Children's Oncology Group (COG) acute lymphoblastic leukemia (ALL) studies to determine if among those who participate in registry studies, there are disparities in participation in therapeutic clinical trials. We hypothesized that minoritized children, those living in disadvantaged neighborhoods, and those living distant from trial sites are less likely to enroll on therapeutic ALL studies.</p>
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Authors: Winestone, Lena E; Gupta, Sumit; Sample, Jeannette; Van Riper, David; Knowles, Katherine; Chen, Zhiguo (Bruce); Jiang, Bo; Velez, Maria C; Loh, Mignon L.; Lupo, Philip J.; Winick, Naomi J; Marcotte, Erin
Periodical (Full): Blood
Issue: Supplement 1
Volume: 142
Pages: 2392
Countries: