MPC Member Publications

This database contains a listing of population studies publications written by MPC Members. Anyone can add a publication by an MPC student, faculty, or staff member to this database; new citations will be reviewed and approved by MPC administrators.

Full Citation

Title: Outcome trajectory estimation for optimal dynamic treatment regimes with repeated measures

Citation Type: Journal Article

Publication Year: 2023

ISSN: 0035-9254

DOI: 10.1093/JRSSSC/QLAD037

Abstract: <p>In recent sequential multiple assignment randomized trials, outcomes were assessed multiple times to evaluate longer-term impacts of the dynamic treatment regimes (DTRs). Q-learning requires a scalar response to identify the optimal DTR. Inverse probability weighting may be used to estimate the optimal outcome trajectory, but it is inefficient, susceptible to model mis-specification, and unable to characterize how treatment effects manifest over time. We propose modified Q-learning with generalized estimating equations to address these limitations and apply it to the M-bridge trial, which evaluates adaptive interventions to prevent problematic drinking among college freshmen. Simulation studies demonstrate our proposed method improves efficiency and robustness.</p>

Url: https://academic.oup.com/jrsssc/advance-article/doi/10.1093/jrsssc/qlad037/7175981

User Submitted?: No

Authors: Zhang, Yuan; Vock, David M; Patrick, Megan E; Finestack, Lizbeth H; Murray, Thomas A

Periodical (Full): Journal of the Royal Statistical Society Series C: Applied Statistics

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IPUMS NHGIS NAPP IHIS ATUS Terrapop