MPC Member Publications

This database contains a listing of population studies publications written by MPC Members. Anyone can add a publication by an MPC student, faculty, or staff member to this database; new citations will be reviewed and approved by MPC administrators.

Full Citation

Title: Neighborhood Differences in Post-Stroke Mortality

Citation Type: Journal Article

Publication Year: 2017

ISSN: 1941-7705

DOI: 10.1161/CIRCOUTCOMES.116.002547

PMID: 28228449

Abstract: BACKGROUND Post-stroke mortality is higher among residents of disadvantaged neighborhoods, but it is not known whether neighborhood inequalities are specific to stroke survival or similar to mortality patterns in the general population. We hypothesized that neighborhood disadvantage would predict higher poststroke mortality, and neighborhood effects would be relatively larger for stroke patients than for individuals with no history of stroke. METHODS AND RESULTS Health and Retirement Study participants aged ≥50 years without stroke at baseline (n=15 560) were followed ≤12 years for incident stroke (1715 events over 159 286 person-years) and mortality (5325 deaths). Baseline neighborhood characteristics included objective measures based on census tracts (family income, poverty, deprivation, residential stability, and percent white, black, or foreign-born) and self-reported neighborhood social ties. Using Cox proportional hazard models, we compared neighborhood mortality effects for people with versus people without a history of stroke. Most neighborhood variables predicted mortality for both stroke patients and the general population in demographic-adjusted models. Neighborhood percent white predicted lower mortality for stroke survivors (hazard ratio, 0.75 for neighborhoods in highest 25th percentile versus below, 95% confidence interval, 0.62-0.91) more strongly than for stroke-free adults (hazard ratio, 0.92; 95% confidence interval, 0.83-1.02; P=0.04 for stroke-by-neighborhood interaction). No other neighborhood characteristic had different effects for people with versus without stroke. Neighborhood-mortality associations emerged within 3 months after stroke, when associations were often stronger than among stroke-free individuals. CONCLUSIONS Neighborhood characteristics predict mortality, but most effects are similar for individuals without stroke. Eliminating disparities in stroke survival may require addressing pathways that are not specific to traditional poststroke care.

Url: http://www.ncbi.nlm.nih.gov/pubmed/28228449

Url: http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=PMC5328121

Url: http://circoutcomes.ahajournals.org/lookup/doi/10.1161/CIRCOUTCOMES.116.002547

User Submitted?: No

Authors: Osypuk, Theresa L; Ehntholt, Amy; Moon, J Robin; Gilsanz, Paola; Glymour, M Maria

Periodical (Full): Circulation: Cardiovascular Quality and Outcomes

Issue: 2

Volume: 10

Pages: e002547

Countries:

IPUMS NHGIS NAPP IHIS ATUS Terrapop