Full Citation
Title: Current Status of Point-of-Care Testing for Human Immunodeficiency Virus Drug Resistance
Citation Type: Journal Article
Publication Year: 2017
ISBN:
ISSN: 0022-1899
DOI: 10.1093/INFDIS/JIX413
NSFID:
PMCID:
PMID: 29040621
Abstract: Healthcare delivery has advanced due to the implementation of point-of-care testing, which is often performed within minutes to hours in minimally equipped laboratories or at home. Technologic advances are leading to point-of-care kits that incorporate nucleic acid-based assays, including polymerase chain reaction, isothermal amplification, ligation, and hybridization reactions. As a limited number of single-nucleotide polymorphisms are associated with clinically significant human immunodeficiency virus (HIV) drug resistance, assays to detect these mutations have been developed. Early versions of these assays have been used in research. This review summarizes the principles underlying each assay and discusses strategic needs for their incorporation into the management of HIV infection.
Url: https://dx.doi.org/10.1093/infdis/jix413
User Submitted?: No
Authors: Duarte, Horacio A.; Panpradist, Nuttada; Beck, Ingrid A.; Lutz, Barry; Lai, James; Kanthula, Ruth M.; Kantor, Rami; Tripathi, Anubhav; Saravanan, Shanmugam; Macleod, Iain J.; Chung, Michael H.; Zhang, Guoqing; Yang, Chunfu; Frenkel, Lisa M.
Periodical (Full): The Journal of Infectious Diseases
Issue: suppl_9
Volume: 216
Pages: S824-S828
Countries: