MPC Member Publications

This database contains a listing of population studies publications written by MPC Members. Anyone can add a publication by an MPC student, faculty, or staff member to this database; new citations will be reviewed and approved by MPC administrators.

Full Citation

Title: Invited commentary: Childhood acute lymphoblastic leukemia and allergies: Biology or bias?

Citation Type: Book, Whole

Publication Year: 2012

ISBN: 0002-9262

ISSN: 00029262

DOI: 10.1093/aje/kws265

PMID: 23171875

Abstract: Previous epidemiologic studies have shown an inverse association between a personal history of atopy/allergies, both overall and among asthma, eczema, and hay fever investigated separately, and childhood acute lymphoblastic leukemia (ALL) with some consistency; however, in most of these studies, exposure data were collected by maternal interview. Now, in a population-based and records-based study in this issue of the Journal (Am J Epidemiol. 2012;176(11):970978), Chang et al. report an increased risk for allergic conditions across different etiologic time periods, calling the former paradigm into doubt. A review of the basic biology literature shows that proposed mechanisms support either a positive or an inverse association. In light of this ambiguity, it is epidemiologys turn to determine the direction of association.

User Submitted?: No

Authors: Linabery, Amy M.; Spector, Logan G.

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Pages: 979-983

Volume: 176

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IPUMS NHGIS NAPP IHIS ATUS Terrapop