MPC Member Publications

This database contains a listing of population studies publications written by MPC Members. Anyone can add a publication by an MPC student, faculty, or staff member to this database; new citations will be reviewed and approved by MPC administrators.

Full Citation

Title: Parental occupational exposure to low-frequency magnetic fields and risk of leukaemia in the offspring: findings from the Childhood Leukaemia International Consortium (CLIC)

Citation Type: Journal Article

Publication Year: 2019

ISSN: 1351-0711

DOI: 10.1136/OEMED-2019-105706

PMID: 31358566

Abstract: Objectives Previously published studies on parental occupational exposure to extremely low-frequency magnetic fields (ELF-MF) and risk of acute lymphoblastic leukaemia (ALL) and acute myeloid leukaemia (AML) in their offspring were inconsistent. We therefore evaluated this question within the Childhood Leukemia International Consortium. Methods We pooled 11 case–control studies including 9723 childhood leukaemia cases and 17 099 controls. Parental occupational ELF-MF exposure was estimated by linking jobs to an ELF-MF job-exposure matrix (JEM). Logistic regression models were used to estimate ORs and 95% CIs in pooled analyses and meta-analyses. Results ORs from pooled analyses for paternal ELF-MF exposure >0.2 microtesla (µT) at conception were 1.04 (95% CI 0.95 to 1.13) for ALL and 1.06 (95% CI 0.87 to 1.29) for AML, compared with ≤0.2 µT. Corresponding ORs for maternal ELF-MF exposure during pregnancy were 1.00 (95% CI 0.89 to 1.12) for ALL and 0.85 (95% CI 0.61 to 1.16) for AML. No trends of increasing ORs with increasing exposure level were evident. Furthermore, no associations were observed in the meta-analyses. Conclusions In this large international dataset applying a comprehensive quantitative JEM, we did not find any associations between parental occupational ELF-MF exposure and childhood leukaemia.

Url: https://oem.bmj.com/content/early/2019/07/29/oemed-2019-105706.abstract

User Submitted?: No

Authors: Talibov, Madar; Olsson, Ann; Bailey, Helen D.; Erdmann, Friederike; Metayer, Catherine; Magnani, Corrado; Petridou, Eleni; Auvinen, Anssi; Spector, Logan G.; Clavel, Jacqueline; Roman, Eve; Dockerty, John D.; Nikkilä, Atte; Lohi, Olli; Kang, Alice Y.; Psaltopoulou, Theodora; Miligi, Lucia; Vila, Javier; Cardis, Elisabeth; Schüz, Joachim

Periodical (Full): Occupational and Environmental Medicine

Issue:

Volume:

Pages: oemed-2019-105706

Countries:

IPUMS NHGIS NAPP IHIS ATUS Terrapop