MPC Member Publications

This database contains a listing of population studies publications written by MPC Members. Anyone can add a publication by an MPC student, faculty, or staff member to this database; new citations will be reviewed and approved by MPC administrators.

Full Citation

Title: Cancer incidence among Minnesota taconite mining industry workers

Citation Type: Journal Article

Publication Year: 2015

ISSN: 10472797

DOI: 10.1016/j.annepidem.2015.08.003

PMID: 26381550

Abstract: PURPOSE To evaluate cancer incidence among Minnesota taconite mining workers. METHODS We evaluated cancer incidence between 1988 and 2010 in a cohort of 40,720 Minnesota taconite mining workers used between 1937 and 1983. Standardized incidence ratios (SIRs) with 95% confidence intervals (CIs) were estimated by comparing numbers of incident cancers with frequencies in the Minnesota Cancer Surveillance System. SIRs for lung cancer by histologic subtypes were also estimated. We adjusted for out-of-state migration and conducted a probabilistic bias analysis for smoking-related cancers. RESULTS A total of 5700 cancers were identified, including 51 mesotheliomas and 973 lung cancers. The SIRs for lung cancer and mesothelioma were 1.3 (95% CI = 1.2-1.4) and 2.4 (95% CI = 1.8-3.2), respectively. Stomach, laryngeal, and bladder cancers were also elevated. However, adjusting for potential confounding by smoking attenuated the estimates for lung (SIR = 1.1, 95% CI = 1.0-1.3), laryngeal (SIR = 1.2, 95% CI = 0.8-1.6), oral (SIR = 0.9, 95% CI = 0.7-1.2), and bladder cancers (SIR = 1.0, 95% CI = 0.8-1.1). CONCLUSIONS Taconite workers may have an increased risk for certain cancers. Lifestyle and work-related factors may play a role in elevated morbidity. The extent to which mining-related exposures contribute to disease burden is being investigated.

Url: http://www.ncbi.nlm.nih.gov/pubmed/26381550

Url: http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=PMC4576455

Url: http://linkinghub.elsevier.com/retrieve/pii/S1047279715003725

User Submitted?: No

Authors: Allen, Elizabeth M; Alexander, Bruce H; MacLehose, Richard F; Nelson, Heather H.; Ramachandran, Gurumurthy; Mandel, Jeffrey H

Periodical (Full): Annals of Epidemiology

Issue: 11

Volume: 25

Pages: 811-815.e1

Countries:

IPUMS NHGIS NAPP IHIS ATUS Terrapop