Full Citation
Title: African American Race Is Associated with Decreased Relapse-Free Survival in Immune Thrombotic Thrombocytopenic Purpura
Citation Type: Journal Article
Publication Year: 2019
ISBN:
ISSN: 0006-4971
DOI: 10.1182/blood-2019-131064
NSFID:
PMCID:
PMID:
Abstract: <p>Background: Immune thrombotic thrombocytopenic purpura (iTTP) is a potentially fatal hematologic disorder characterized by thrombocytopenia, microangiopathic hemolytic anemia, and ischemic organ impairment. The incidence of iTTP is higher among African-Americans (AA), however, differences in presentation and outcomes have not been fully investigated. In a multi-center cohort of patients with iTTP from the United States Thrombotic Microangiopathy (USTMA) Consortium, we tested the hypothesis that AA race is an independent predictor of poor outcomes including iTTP related mortality and relapse.</p>
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Authors: Liu, Angela; Mazepa, Marshall; Davis, Elizabeth E; Johnson, Andrew; Antun, Ana G.; Farland, Andrew M.; Woods, Ryan R; Metjian, Ara D; Bagby, Kristin; Park, Yara; Raval, Jay S; de Ridder, Gustaaf; Gibson, Briana; Kasthuri, Raj S.; Liles, Darla K; Eubanks, Susan; Akwaa, Frank; Baumann Kreuziger, Lisa; Sadler, J. Evan; Sridharan, Meera; Go, Ronald; Kohli, Rahil; Upreti, Harsh Vardhan; McCrae, Keith R; Lim, Ming Y.; Zheng, X. Long; Kocher, Nicole K.; Gangaraju, Radhika; Cataland, Spero; Chaturvedi, Shruti
Periodical (Full): Blood
Issue: Supplement_1
Volume: 134
Pages: 1066-1066
Countries: