MPC Member Publications

This database contains a listing of population studies publications written by MPC Members. Anyone can add a publication by an MPC student, faculty, or staff member to this database; new citations will be reviewed and approved by MPC administrators.

Full Citation

Title: Genetic and nongenetic risk factors for childhood cancer

Citation Type: Book, Whole

Publication Year: 2015

ISBN: 9780323354486

ISSN: 15578240

DOI: 10.1016/j.pcl.2014.09.013

PMID: 25435109

Abstract: The causes of childhood cancer have been systematically studied for decades, but apart from high-dose radiation and prior chemotherapy there are few strong external risk factors. However, inherent risk factors including birth weight, parental age, and congenital anomalies are consistently associated with most types of pediatric cancer. Recently the contribution of common genetic variation to etiology has come into focus through genome-wide association studies. These have highlighted genes not previously implicated in childhood cancers and have suggested that common variation explains a larger proportion of childhood cancers than adult. Rare variation and nonmendelian inheritance may also contribute to childhood cancer risk but have not been widely examined.

User Submitted?: No

Authors: Spector, Logan G.; Pankratz, Nathan; Marcotte, Erin L.

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Pages: 11-25

Volume: 62

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IPUMS NHGIS NAPP IHIS ATUS Terrapop