MPC Member Publications

This database contains a listing of population studies publications written by MPC Members. Anyone can add a publication by an MPC student, faculty, or staff member to this database; new citations will be reviewed and approved by MPC administrators.

Full Citation

Title: Importance of human milk for infants in the clinical setting: Updates and mechanistic links

Citation Type: Journal Article

Publication Year: 2023

ISSN: 1941-2452

DOI: 10.1002/NCP.11037

PMID: 37721461

Abstract: INTRODUCTION: Human milk (HM) is the optimal source of nutrition for infants and has been implicated in multiple aspects of infant health. Although much of the existing literature has focused on the individual components that drive its nutrition content, examining HM as a biological system is needed for meaningful advancement of the field. Investigation of the nonnutritive bioactive components of HM and the maternal, infant, and environmental factors which affect these bioactives is important to better understand the importance of HM provision to infants. This information may inform care of clinical populations or infants who are critically ill, hospitalized, or who have chronic diseases and may benefit most from receiving HM. METHODS: In this narrative review, we reviewed literature examining maternal and infant influences on HM composition with a focus on studies published in the last 10 years that were applicable to clinical populations. RESULTS: We found multiple studies examining HM components implicated in infant immune and gut health and neurodevelopment. Additional work is needed to understand how donor milk and formula may be used in situations of inadequate maternal HM. Furthermore, a better understanding of how maternal factors such as maternal genetics and metabolic health influence milk composition is needed. CONCLUSION: In this review, we affirm the importance of HM for all infants, especially clinical populations. An understanding of how HM composition is modulated by maternal and environmental factors is important to progress the field forward with respect to mechanistic links between HM biology and infant health outcomes.

Url: https://onlinelibrary.wiley.com/doi/full/10.1002/ncp.11037

Url: https://onlinelibrary.wiley.com/doi/abs/10.1002/ncp.11037

Url: https://aspenjournals.onlinelibrary.wiley.com/doi/10.1002/ncp.11037

User Submitted?: No

Authors: Nagel, Emily M.; Elgersma, Kristin M.; Gallagher, Tiffany T.; Johnson, Kelsey E.; Demerath, Ellen; Gale, Cheryl A.

Periodical (Full): Nutrition in Clinical Practice

Issue:

Volume: 38

Pages: S39-S55

Countries:

IPUMS NHGIS NAPP IHIS ATUS Terrapop