MPC Member Publications

This database contains a listing of population studies publications written by MPC Members. Anyone can add a publication by an MPC student, faculty, or staff member to this database; new citations will be reviewed and approved by MPC administrators.

Full Citation

Title: Using contact patterns to inform HIV interventions in persons who inject drugs in northern Vietnam

Citation Type: Journal Article

Publication Year: 2018

ISSN: 10779450

DOI: 10.1097/QAI.0000000000001632

Abstract: Objectives: Population mixing patterns can greatly inform allocation of HIV prevention interventions such as treatment as prevention or preexposure prophylaxis. Characterizing contact patterns among subgroups can help identify the specific combinations of contact expected to result in the greatest number of new infections.; Setting: Baseline data from an intervention to reduce HIV-related risk behaviors in male persons who inject drugs (PWID) in the Northern Vietnamese province of Thai Nguyen were used for the analysis.; Methods: Egocentric network data were provided by PWID who reported any drug-injection equipment sharing in the previous 3 months. Age-dependent mixing was assessed to explore its epidemiological implications on risk of HIV transmission risk (among those HIV-infected) and HIV acquisition risk (among those not infected) in PWID.; Results: A total of 1139 PWID collectively reported 2070 equipment-sharing partnerships in the previous 3 months. Mixing by age identified the 30-34 and 35-39 years age groups as the groups from whom the largest number of new infections was transmitted, making them primary targets for treatment as prevention. Among the uninfected, 25-29, 30-35, and 35-39 years age groups had the highest HIV acquisition rate, making them the primary targets for preexposure prophylaxis.; Conclusions: Collection and analysis of contact patterns in PWID is feasible and can greatly inform infectious disease dynamics and targeting of appropriate interventions. Results presented also provide much needed empirical data on mixing to improve mathematical models of disease transmission in this population.;

User Submitted?: No

Authors: Smith, Kumi; Graham, Matthew; Latkin, Carl A.; Go, Vivian L.

Periodical (Full): Journal of Acquired Immune Deficiency Syndromes

Issue: 1

Volume: 78

Pages: 1-8

Countries:

IPUMS NHGIS NAPP IHIS ATUS Terrapop